I think the reason that these two civilizations have such a powerful effect on the reader is that they are exploring these concepts. The other civilizations, have their own core values, but they don't tend to be exploring them to such a degree (and, in some cases, are actively resisting exploration into what it means to be human). Some, such as the Rationalist League, have even realised that they might have made a mistake. It is no wonder that these two civilizations seem to form the core of the two major opposing alliances in the game.
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I think the reason that these two civilizations have such a powerful effect on the reader is that they are exploring these concepts. The other civilizations, have their own core values, but they don't tend to be exploring them to such a degree (and, in some cases, are actively resisting exploration into what it means to be human). Some, such as the Rationalist League, have even realised that they might have made a mistake. It is no wonder that these two civilizations seem to form the core of the two major opposing alliances in the game.